山东大学研究生导师介绍------王金星
王金星，山东大学生命科学学院动物学、生化与分子生物学教授。分别于1984年和1998年获动物学硕士和博士学位。1984年硕士研究生毕业留校工作至今。在此期间，1992年作为访问学者到日本山口大学学习和工作，2001年获德国研究协会（dfg）资助，到德国吉森大学进行合作研究，2000年获日本九州工业大学外国研究者奖学金，到九州工业大学进行合作研究。研究方向：无脊椎动物先天免疫
主要包括：1 免疫防御相关基因的的鉴定
2 抗菌肽在先天免疫防御中的作用
3 先天免疫的模式识别受体
dr. jin-xing wang, professor of zoology, biochemistry and molecular biology, school of life sciences, shandong university. he received his msc (1984) and phd (1998) in zoology. he was awarded a scholarship of dfg (2001, working in giessen university, germany) and scholarship for foreign researcher of kit (2000, working in kyushu institute of technology, japan). he is also a visiting scholar in yamaguchi university (japan, 1992).
major research interest: innate immunity of invertebrates
invertebrates are believed to lack adaptive immunity and to depend completely on their innate immune system, including humoral and cellular immune reactions, to defense microorganisms. his group is studying the innate immunity of invertebrates (penaeid shrimp and housefly) in order to understand the mechanisms of invertebrate immunity. the interested areas of the research include:
1 identification of genes involved in immune response to pathogens;
2 role of antimicrobial peptides in innate immune defense responses.
3 pattern recognition receptors that are responsible for the initial self/non-self recognition.
seleted publications(* correspond author):
kang c-j, wang j-x*, zhao xf, yang xm, shao hl, xiang jh. molecular cloning and expression analysis of ch-penaeidin, an antimicrobial peptide from chinese shrimp, fenneropenaeus chinensis. fish shellfish immunol. 2004, 16(4):513-25.
wang j-x*, zhao x-f progress in pattern recognition receptors of innate immunity in invertebrate. prog. biochem. biophys. 2004, 31(2): 112-117
li l, wang j-x*, zhao x-f, kang cj, liu n, et al., high level expression, purification, and characterization of the shrimp antimicrobial peptide, ch-penaeidin, in pichia pastoris. protein expr purif. 2005, 39(2):144-51.
li d-x, du x-j, zhao x-f, wang j-x* cloning and expression analysis of an o-methyltransferase (omt) gene from chinese shrimp, fenneropenaeus chinensis. fish shellfish immunol. 2006, 21(3):284-92
du x-j, wang j-x*, liu n, zhao x-f, li f-h, xiang j-h. identification and molecular characterization of a peritrophin-like protein from fleshy prawn (fenneropenaeus chinensis). mol immunol. 2006, 43: 1633–1644
sun y-d, zhao x-f, kang c-j, wang j-x*. molecular cloning and characterization of fc-tsp from the chinese shrimp fenneropenaeus chinensis. mol immunol. 2006, 43: 1202–1210
liang y-l, wang j-x*, zhao x-f, du x-j, xue j-f. molecular cloning and characterization of cecropin from the housefly (musca domestica), and its expression in escherichia coli.dev comp immunol. 2006;30(3):249-257.
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